ISSN 0253-2778

CN 34-1054/N

Open AccessOpen Access JUSTC Research Article

Bayesian variable selection for proportional hazards model with current status data

Cite this:
https://doi.org/10.3969/j.issn.0253-2778.2020.10.003
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  • Author Bio:

    Cui Di: PhD cadidate.Research field:Statistical model. E-mail:cuidi@mail.ustc.edu.cn

  • Corresponding author: Zhang Weiping: Corresponding author, PhD/professor. Research field:Statistical learning theory.E-mail:zwp@ustc.edu.cn
  • Received Date: 12 September 2020
  • Rev Recd Date: 20 October 2020
  • Publish Date: 31 October 2020
  • A Bayesian proportional hazards (PH) model is proposed for analyzing current status data based on Expectation-Maximization Variable Selection (EMVS) method. This model can estimate parameters and select variables simultaneously, which efficiently improves model interpretability and predictive ability. To identify risk factors, appropriate priors are assigned on the indicator variables that denote the existence of covariates. The baseline cumulative hazard function is approximated via monotone splines. A novel Expectation-Maximization (EM) algorithm is developed for model fitting by using a two-stage data augmentation procedure involving latent Poisson variables. Finally, the performance of proposed method is investigated by simulations and a real data analysis.
    A Bayesian proportional hazards (PH) model is proposed for analyzing current status data based on Expectation-Maximization Variable Selection (EMVS) method. This model can estimate parameters and select variables simultaneously, which efficiently improves model interpretability and predictive ability. To identify risk factors, appropriate priors are assigned on the indicator variables that denote the existence of covariates. The baseline cumulative hazard function is approximated via monotone splines. A novel Expectation-Maximization (EM) algorithm is developed for model fitting by using a two-stage data augmentation procedure involving latent Poisson variables. Finally, the performance of proposed method is investigated by simulations and a real data analysis.
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