ISSN 0253-2778

CN 34-1054/N

Open AccessOpen Access JUSTC

Research progress on the role of lncRNA HULC in tumors

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https://doi.org/10.3969/j.issn.0253-2778.2018.10.007
  • Received Date: 17 May 2018
  • Rev Recd Date: 28 June 2018
  • Publish Date: 31 October 2018
  • In recent years, with the rapid development of molecular biology research, increasing attention has been paid to long non-coding RNA (lncRNA) ,whose role in tumor occurrence, development, treatment and prognosis has also been gradually recognized. HULC (highly up-reglated in liver cancer) is a type of lncRNA called liver cancer highly expressed transcript, which was first discovered in liver cancer. Recent studies have revealed that it is also closely related to many other cancers such as gastric cancer, colorectal cancer, osteosarcoma and diffuse large B-cell lymphomas . This paper reviewed the research progress of HULC expression and its mechanism of action in several different tumor tissues.
    In recent years, with the rapid development of molecular biology research, increasing attention has been paid to long non-coding RNA (lncRNA) ,whose role in tumor occurrence, development, treatment and prognosis has also been gradually recognized. HULC (highly up-reglated in liver cancer) is a type of lncRNA called liver cancer highly expressed transcript, which was first discovered in liver cancer. Recent studies have revealed that it is also closely related to many other cancers such as gastric cancer, colorectal cancer, osteosarcoma and diffuse large B-cell lymphomas . This paper reviewed the research progress of HULC expression and its mechanism of action in several different tumor tissues.
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