Abstract: A two-sided comb-type pilot structure generated using Golay complementary sequence and time-domain channel estimation is proposed for MIMO SC-FDMA systems under time-varying frequency selective fading channels. Both left-shift and right-shift fast periodic Golay correlation lattices are combined as a symmetrical lattice. It can be used to efficiently implement periodic correlations of phase-shift and sequence orthogonal comb-type pilot blocks in the time domain. Employing this special lattice, computational complexities are significantly reduced. Low-complexity algorithm can reduce power consumption of a processor, which meets one of the requirements of green communications. Simulation results demonstrate the performance merits of the proposed scheme.